This is my working hypothesis - the way I see it as of this moment!!

names appears as Winn, Wynn, Wynns and Wynne in the early records

observations:  If Rose Bush is the mother of  all of George Wynns's children she would have  been born ca 1685 as John Wynns was born in 1702. 
1702 son John was  born [from deputation]
1716 son Benjamin was born [from deputation]
1718 George Wynns bought land in Chowan County
1719 George Wynne served on the Grand Jury
1720  grant from the Lord Proprietors 400 acres (in what was later Bertie County)
1719-21 Queen Ann's Creek, Justice of the Peace, Clerk of the Court, Bertie  Precinct   under the proprietary Governor (Col. Rec. pp 275-285). 
1727 Called Capt. George Wynne 
1731 - 1737   represented Bertie County in the Colonial General Assembly 
May 1751 George Wynns inventory was handed in  by William Wynns and Benjamin Wynns, exrs. [Bertie County] 

Aug 1753 John Wynns - Inventory by Benjamin Wynns and William Wynns, exrs.
1757 Bertie County Tax List 
   at the end of Jno Hill's List - Benjamin Wynns -9
   A List of Taxables taken by me William Wynns, one of his majestyes Justice of the Peace for Bertie Co for the year Amno Dom 1757: 
     Joseph Wynns, Polliasiah Wynns - Sam - 3
     Culmer Sesseans, Cullen Sesseans, John Sesseans - Pompy, Nann, Pompy - 6
     Burrell Bell - Phillip, Cesar, Tom, Kadar, Mingo, Bett, Nann, Priss, Amah - 10
  List by Jos. Jordan
     Jas. Boon Winns - Negroes Charley, Moll, Jacob - 3
Apr 15 1758 - William Wynns dead - request to sell perishable estate of the dec'd by Benjamin Wynns, John Harrell and Elizabeth Wynns [widow of the dec'd]

1768/70 William Murfree's Tax Receipt Book Hertford Co.
  Benjamin Wynns
   1768  21 Taxes plus a chair with 2 wheels
   1769 24 Taxes plus a chair with 2 wheels
   1770 22 Taxes

    Joseph Wynns 
     1768 4 Taxes
     1769 4 Taxes
     1770 2 Taxes

   Geo/r/ .. Paletiah Wynns
     1770 1 Tax

    John Augs. Wynns
    1768 4 Taxes
    1769 4 Taxes
    1770 2 Taxes

1779 Tax List Hertford Co
  William Wynns   320 a, 19 negroes, 4 horses, 100 a,  money in trade 5000 pds
   Thomas Wynns  money and stock in trade 2700 pds, 4 negroes, 4 mares, 
   John Augustus Wynns 1 plantation, 2 negroes, 3 horses, 5 cattle
   Benjamin Wynns  600 a D C Mill, 100 a  Hickory Neck, 398 a Long Pocoson,  200 a F Brown, 
     670 a manor Plantation, Golfs, Red Banks, old Place, 100 a meadow land, 100 a Chamblee's, 100 a Pocoson Gates Co, 50 a hale Winton Land, 50 a. half Pine Tree Store, 3 half acre lots in Winton, 250 a Scull's place, 200 a joining the above,  23 negroes,  32 cattle, 5 horses [the best dead] one more dead,
 money 300 pds.
   George Wynns  720 a, 100 a., 7 horses,  10 cattle, 16 slaves, stock in trade 7500 pds, money at int 600 pds, money in hand 500 pds

1784 Tax List Hertford Co  NCGSJ-Aug 83 
  Benj. Wynns 923 a Hertford +2 lots Winton - 1 fp - 7 bp
  John A Wynns 200 a Hertford - 1 fp - 3 bp
  Thomas Wynns 988 a Hertford - 1 fp - 6 bp
  Capt Wm B Wynns 640 a Hertford - 1fp - 5 bp
  William Wynns 50 a Hertford + 2 town lots - 1 fp - 14 bp
  Col. George Wynns 1062 a Hertford + 5 lots Winton - 1 fp - 9 bp

Rose Bush was daughter of William Bush & wife, Martha Hill, of Isle of Wight County, VA..   

Children of George Wynn & Rose Bush:
1. John Wynns  ca 1702 - ca 1750/53
       Deputy Clerk of the Court of Bertie County in 1741 aged 39
       Inventory Aug 1753 by Benjamin Wynns and William Wynns, exrs.
        married 1st Mary Boone ca 1712 - daughter of James & Elizabeth
        married 2nd Sarah VanPelt died 6 Nov 1758
            Sarah married 2nd 18 July 1753 Burrill Bell d.1760
2. Mary Wynns died bef 1764
       married Culmer Sessums ca 1710 - 1772
3. Benjamin Wynns  ca 1716 - 1777?
                carpenter [1748]
      married Catherine Baker est 1720 -
            (dau of Henry Baker died 1770 & Catherine Booth)
      married 2nd Margaret Pugh
            (dau. of Col. Francis Pugh and Pherabe Savage)
4. Joseph Wynns ca 1717 - will Aug 1771 Hertford Co - granted to Benjamin Wynns
           millwright
     married Judith Perry 
             dau of William Perrey  
5. Sarah Wynns  d aft 1779
     married ca 1740 Peter Evans ca 1720 - 1761 Hertford Co
           carpenter  
           son of Robert Evans 1690 -1745 and Ann Hooker dau of William
6. William Wynns  died bef 15 April 1758   merchant
      married 2 Jan 1752 Zilpah Speight [Blanchard] ? - ca 1753
              widow of Aaron Blanchard of Chowan Co
      married ca 1754 Elizabeth Deans
7. George Wynns 1728/31 -  removed from county ca 1755
             1st signs as wit to deed Nov Ct 1749  Bertie Deeds
             sells property  
              G 497 - 6 Nov 1752 George Wynns to William Askew
              G 507 George Wynns to William Wright, School Master - 5 June 1752 May Ct 1753
              H 211 Aaron Askew, Planter to Benjamin Wynns 19 July 1755  - Wit: George Wynns

Bertie Deed Book I page 274: Deposition of Benjamin Wynns, age 43, of Bertie Co. He stated that Robert Warrin late of sd county is heir to William Warrin dec'd of sd county & in possession of land on Wiccacon Creek joining Horse Swamp, James Harris, James Sparkman, John Early; that sd. William Warrin possessed the land 20 years before he died. Aprl. Ct. 1759. Ordered to be registered. cc: Benjn. Wynns.

Will: George Wynns 2 Feb 1750/51 proved May Ct 1751
 "..being sick and weak of body."
 Eldest son John Wynns - two shillings and sixpence, Negroes Gesse mona and Toby.
 Eldest daughter Mary Sessums (wife of Culmer Sessums) - two shillings and sixpence and Negro Pompey. 
Son Joseph Wynns - four pounds, two shillings and sixpence, negroe Peter, reserving the use of said Negro for my wife Rose Wynns for her lifetime.
 Son Benjamin Wynns - two shillings and sixpence and Negroes Bett, Harry and Jemima. 
 Son William Wynns - two shillings and sixpence and Negroes Cotton and Hagar, reserving their use for my wife during her lifetime. 
 Daughter Sarah Evans (wife of Peter Evans) - two shillings and sixpence, Negro Jemmey for her lifetime and at her death to fall to Benjamin Evans son of the said Sarah and Peter Evans. 
 Son George Wynns -two shillings and sixpence and land and plantation where I now live, reserving the use of such to my wife during her lifetime, also Negroes Cezar, Hannah, Cate and Issac, but reserving the use of Cezar for my wife during her lifetime. 
 Remaining personal estate to my wife Rose Wynns for her lifetime and at her death to be divided among my seven children John Wynns, Mary Sessums, Joseph Wynns, Benjamin Wynns, William Wynns, Sarah Evans and George Wynns. 
Ex: sons Benjamin and William  
Wit: John Baker, Thos. Lee, John Harrell, James Boon.