Mayer MAYER 1790 - ca 1855 | his parents
&  unknown 1st wife ca 1800 - ca 1830 | her parents
& Babette Grunebaum 1805 - 1885 | her parents
of Neidenstein, Germany 

This is my working hypothesis - the way I see it as of this moment!! 

Child of Mayer Mayer and first wife:
1. Esther Mayer 1821 - 31 Aug 1899 Jersey City, NJ
   married Hayum Joseph Mayer 1817 Frankfort Ger - 18 Sept 1899 Jersey City NJ

Children of Mayer Mayer and Babette Grunebaum
2. Ernestine (Ester) Mayer 9 Jan 1833 - 5 Feb 1874
    married Joanthan Mayer 27 Feb 1827 - 14 Dec 1908 N, Ger.
3. Joseph H. Mayer 27 Jan 1834 N Ger - 14 Nov 1914 Jersey City, NJ
        Joseph H Mayer came to America with his cousins, Isaac and Ernestine, Ernestine's first husband Moses Mayer and his sister Caroline, arriving in New York on 15 Nov 1853 on the "Fortitude" from Harve.
    married ca 1858 Lena Baum
     a. Pauline Mayer 8 Aug 1859 - 29 Sept 1922 Switzerland
         married 1880 Gustave Mayer 28 Dec 1849 - 25 June 1921
     b. Simon Mayer 8 Aug 1859 - 
         married 1894 Rose -----
          i. Beatrice Mayer 1895 -
              married NYC 1915 Mr Lamm
         ii. infant 1896 - dy
        iii. Florence Mayer 1897 -
             married NYC 1920 Milton Joseph
         iv. infant 1898 -  dy
         v. Murray Mayer 1899 NYC -
         vi. Violet Mayer 1902 NYC -
               married 1923 Milton Wertheim
         vii. Larry Mayer 1903 NYC -
     c. Flora Mayer 1863 - 1922 NYC
         married 1880 Harry Lowenstein 1860 -
           i. Birdie Lowenstein 1882 NYC -
              married 1904 Dave Soman
           ii. Jerome Lowenstein 1884 -
     d. Bertha Mayer 23 May 1865 - 2 Dec 1946 NYC
         married 1890 Max Klipper
     e. David Mayer 12 Oct 1868 Jersey City NJ - 15 July 1941 NYC
         married 1892 Bella Kahn 27 Aug 1872 - 27 July 1946
           i. Miriam Mayer 19 Dec 1892 - 16 Oct 1972
              married Myron Nathan 15 Oct 1887 Jersey City - 22 Apr 1965
                   1. Charles M Nathan 5 Dec 1915 -
     f. Sadie Mayer 6 Feb 1873 Jersey City NJ - 17 Aug 1896
     g. Stella Mayer 1874 -
         married Selig
    Joseph H married 2nd ca 1902 Sara ?
4. Sophie Mayer ca 1839 - 
       married Nathan Wolf-Wolf Nathan 1824 -
5. Kaufmann Kafel (Zadok) Mayer 11 Nov 1839 N Ger - 16 Feb 1913 N Ger.
        married ca 1859 Auguste (Gustl) Mayer 11 Oct 1841 N Ger - 27 Feb 1913 N Ger
             daughter of Mayer Mayer The Younger
      a. Rosa Mayer 1861 N Ger. - 
      b. Lisette Mayer 1864 N Ger - 1943 [concentration camp]
           married David Keller of Adelsheim
      c. Joseph Mayer III
      d. Thekla Mayer
6. Isak (Isaac) Mayer 4 Apr 1842 - 16 May 1911
     married 1867 Adelheid Haber 1845 Richen Ger - 22 Apr 1899
      a. Hannchen Mayer 24 Aug 1868 N Ger - ca 1941
           married Samuel Ottenheimer
      b. Joseph Mayer II 10 Jan 1870 N Ger - 2 Mar 1928
           married 1902 Ida Mayer 12 Feb 1879 N Ger - 10 May 1971 NYC
           i. Paula Mayer Mar 1904 - June 1904
           ii. Adelheid Mayer Mar 1904 - 18 July 1904
          iii. Betty Mayer 
                    1. Susan Ulmann 1938 NYC -
          iv. Adelheid Ada Mayer 2 Dec 1912 - ca 1915
      c. Emilia
      d. Pauline Mayer 1 Jan 1873 - 1 Sept 1873  dy
      e. Lena Mayer 27 Mar 1874 N Ger -
      f. Adolph Mayer 11 Nov 1875 N Ger - 1 Dec 1878 dy
      g. Louis Mayer 9 June 1877 N Ger - 24 Aug 1877 dy
      h. Theodore Mayer 15 Mar 1880 N Ger - 25 Sep 1880 dy
      i. Karl Mayer 25 Aug 1881 N Ger  - 1935
          married ca 1902 Fanny Reis 
           i. Hans Mayer 26 Jan 1914 - 1940
                  [deported, died in concentration camp]
          ii. Friedel [Frieda] Mayer 21 Aug 1919 -
                "left Germany in 1940 with very little, like many, of course. She travelled via Yugoslavia  (the tragic Kladovo Transport) to Palestine,  later joined the British Army in Egypt, where she met my father and eventually decided to marry him and live in England."
              married aft 1940 William Hawkin 9 Oct 1920 -
                    1. Frances Hawkin Ipson 1949 England -

                    2. David Hawkin 1954 England -
         iii. Annelise Mayer 22 Aug 1926 -
                   "escaped at 14 years old through Switzerland"
              married ca 1945 Joseph Cohen ca 1925 -
                     1. Ziporah Cohen 1947 -
                     2. Moshe Cohen 1948 -
                     3. Dvorah Cohen 1951 -
      j. Morritz Mayer 10 Feb 1884 N Ger - 7 May 1885 dy
      k. Berta Mayer 21 Aug 1887 N Ger - 25 Oct 1929
           married ca 1910 Alfons Mannheimer born in Eltsville [near Frankfort]
            i. Alfred Mannheimer 24 June 1914 - 1942 [deported, died in concentration camp]
           ii. Kurt Mannheimer 31 Dec 1915 -
               married ca 1935 Bessie
           iii. Ernst Mannheimer 5 July 1917 -
           iv. Walter Mannheimer 15 May 1919 - 1943 [died in concentration camp]
           v. Hilde Mannheimer 13 Sept 1920 -
               married Salam Goldberg
           vi. Fritz Mann [Micha] Mannheimer 27 Feb 1923 -
                married ca 1943 Hilda Kersten
           vii. Otto Mannheimer
          viii. Gunther Mannheimer
7. Emma Mayer 4 Oct 1844 - 30 Sept 1922 New York City
     married Ferdinand Bamberger
8. Fanny Mayer 1860 - 1914 Pforzheim, Ger.
     married Solomon Hobach d 1907   [had nine daughters]

 
Eight of the nine daughters in Grosseicholzheim Baden 
2nd from left Thekla and 3rd from left Getta

      a. Frederika Hobach 7 May 1875 Grosseicholzheim Baden - 22 Sep 1939 Germany
           married ca 1895 David Scheurermann   [2 sons & 3 daughters]
                        6 April 1865 Binan Am Necker Ger - 5 May 1940 Berlin Germany
            i. Oscar  lived Israel
                married Lore
                     1. Judith
                     2. Michal
                     3. David
           ii. Klara    USA
                married Karl Tiefenbronner
                      1. Margaret
                           a. Judy   USA
          iii. Irmel Schlimmer    Israel
                      1. Hanna Schild
                            a. Peter   USA
          iv. Bertel Krauskopf  --- Israel
                     1. Inge     -- lived in France
           v. Max    USA
                married Hilde
                      1. Fritz/Fred
                      2. Hanna Step
      b. Matilda Hobach ca 1877 Grosseicholzheim Baden [Ger] - ca 1947 Montevideo Uraguay
           married ca 1897 Daum Keilsheim
      c. Thekla Hobach 1879 - 1959 Israel    [3 daughters]
           married ca 1901 Emmauel/Emil Tiefenbronner 1875 - 1959 of Pforzheim Ger -
                 came to Israel in 1939
            i. Irma 1905 - 1995
                married Herman Hirchheimer
                       1. Jack 1934 - 2008
                            married Margie [2 sons]
           ii. Bertel 1907 - 1991
                married Fred Demburg   [no children]
          iii. Else 1911 - 1988  Israel
                 married Hans Dalman [2 daughters]
                        1. Ronit 1944
                            married Nissim Mitrani  -- Israel
                       2. Nurith 1939 - 2004
                             married Reuven Goetz

 
50th Anniversary Party of Emil and Thekla [seated] showing the whole family in Israel

      d. Betty Hobach ca 1880 - 1911 [child birth]
           married Julius Stern of Wieseck, Hesse, Ger. -   5 children
      e. Getta Hobach  1881 Pforzheim Ger - 1936 Pforzheim Ger [2 sons 1 dau]
           married ca 1903 Julius Tiefenbronner  [brother of Emil] of Pforzheim Germany
           i. Ilse 1908 - 1993   Israel & USA
              married Armin Steiner 1903 - 1974
                      1. Gitta 1943 [3 children]
           ii. Sigfried/Stanley 1914 - 1982  USA
               married Lore
                       1. Carol 1951 [2 children]
           iii. Hans/Harry 1919 - [one of twins]  USA
                married Edith [two children]
                        1. Steven 1949 -
                        2. Terry 1958 [one son]
           iv. Eric 1919 - 1919 [one of twins]
                    lived only a few weeks
      f. Pauline Hobach ca 1883 - ca 1927    [2 dau and a son]
           married ca 1899 Selig Scheuermann of Frankfort, Am Main, Germany
            i. Grete Meyer   USA
      g. Tilly Hobach   [2 sons and 2 daughters]
            married ca 1905 Gustav Weil of Steinfurt, Baden, Ger. -
             i. Poldi    USA [2 children]
                married Margaret USA
                       1. Gary
                       2. Helen
            ii. Sigi    USA [2 children]
                       1. son Terry  
                       2. daughter Marilyn
           iii. Else       South America
           iv. Florte     South America
      h. Emma Hobach ca 1890 Grosseicholzheim Baden - ca 1940 Israel  [2 sons]
            married ca 1910 Rudolph Haarburger ca 1890 Lautershausen Baden Ger -
            i. Shlomo
                married Anuga [1son & 1 daughter] Israel
            ii. Reuven
                married Gina [2 sons]
      i. Lina Hobach ca 1892 Grosseicholzheim Baden - 17 Dec 1967 Chicago IL
         married ca 1915 Adopf Ottenheimer